ITLN2

Across TCGA cell cohorts, ITLN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 894 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ITLN2-associated GO terms across cancer lineages are Glutathione derivative biosynthetic process, Regulation of pH, and Negative regulation of cell maturation. Each is linked with ITLN2 in more than 3 cancer types. Because this analysis shows association rather than direction, both ITLN2-to-partner and partner-to-ITLN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glutathione derivative biosynthetic process grouped by ITLN2-low versus ITLN2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITLN2→partner) and Y-score (partner→ITLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Glutathione derivative biosynthetic process →	+0.174	+0.079	<.001	.009	3	3
SKIN	Regulation of pH →	+0.067	+0.629	<.001	.001	3	3
SOFT_TISSUE	Negative regulation of cell maturation →	+0.726	+0.035	.005	.008	2	4
BREAST	Cell communication involved in cardiac conduction →	+0.145	+0.101	.005	.004	3	3
BREAST	Actin filament-based transport →	+0.076	+0.067	.005	.005	3	3
SKIN	Endoderm development →	-0.110	-0.649	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 894 associations by consensus.

Glutathione derivative biosynthetic process by ITLN2 expression — OESOPHAGUS

Explore this box plot interactively →