ITLN1

Across TCGA patient cohorts, ITLN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,980 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ITLN1-associated GO terms across cancer lineages are Detoxification, Phosphatidylcholine metabolic process, and Long-chain fatty acid metabolic process. Each is linked with ITLN1 in more than 14 cancer types. Because this analysis shows association rather than direction, both ITLN1-to-partner and partner-to-ITLN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Detoxification grouped by ITLN1-low versus ITLN1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITLN1→partner) and Y-score (partner→ITLN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Detoxification →	+0.036	+1.994	<.001	<.001	3	15
UCS	Phosphatidylcholine metabolic process →	+0.032	+1.346	<.001	<.001	3	15
STAD	Long-chain fatty acid metabolic process →	+0.036	+1.661	<.001	<.001	3	15
ESCA	Glycerol ether metabolic process →	+0.069	+2.169	<.001	<.001	3	14
SCLC	Humoral immune response →	+0.159	+1.117	<.001	.003	3	14
STAD	Response to toxic substance →	+0.024	+1.198	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,980 associations by consensus.

Detoxification by ITLN1 expression — STAD

Explore this box plot interactively →