ITLN1

Across TCGA cell cohorts, ITLN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 886 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ITLN1-associated GO terms across cancer lineages are Formation of cytoplasmic translation initiation complex, Regulation of NMDA receptor activity, and Natural killer cell chemotaxis. Each is linked with ITLN1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ITLN1-to-partner and partner-to-ITLN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Formation of cytoplasmic translation initiation complex grouped by ITLN1-low versus ITLN1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITLN1→partner) and Y-score (partner→ITLN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Formation of cytoplasmic translation initiation complex →	+0.092	+0.735	<.001	.003	3	4
BLOOD_Leukemia	Regulation of NMDA receptor activity →	+1.036	+0.530	<.001	<.001	3	4
BLOOD_Leukemia	Natural killer cell chemotaxis →	-0.298	-0.637	<.001	.007	3	4
BLOOD_Leukemia	Ductus arteriosus closure →	+1.001	+0.862	<.001	.002	3	4
BLOOD_Lymphoma	Regulation of lactation →	+0.150	+0.026	.002	.009	3	4
CNS	Cholesterol homeostasis →	+0.035	+0.097	.002	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 886 associations by consensus.

Formation of cytoplasmic translation initiation complex by ITLN1 expression — BLOOD_Leukemia

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