ITIH2

Across TCGA patient cohorts, ITIH2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,032 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ITIH2-associated genes across cancer lineages are SERPINE1, TGFB3, and GFPT2. Each is linked with ITIH2 in more than 7 cancer types. Because this analysis shows association rather than direction, both ITIH2-to-partner and partner-to-ITIH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITIH2 versus SERPINE1 in OV, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITIH2→partner) and Y-score (partner→ITIH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SERPINE1 →	+1.428	+0.577	<.001	<.001	3	8
OV	TGFB3 →	+1.207	+0.699	<.001	<.001	3	8
OV	GFPT2 →	+1.238	+0.589	<.001	.001	3	8
BRCA	LRRC32 →	+0.904	+0.585	<.001	<.001	3	8
COAD	THY1 →	+0.993	+0.901	<.001	<.001	3	8
COAD	COL1A2 →	+1.788	+0.784	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,032 associations by consensus.

ITIH2 vs SERPINE1 — OV

Explore this scatter interactively →