ITIH1

Across TCGA patient cohorts, ITIH1 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,945 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ITIH1-associated proteins across cancer lineages are VAV1, WAS, and GPSM3. Each is linked with ITIH1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ITIH1-to-partner and partner-to-ITIH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITIH1 versus VAV1 in LSCC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITIH1→partner) and Y-score (partner→ITIH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	VAV1 →	+0.481	+0.159	<.001	<.001	3	4
LSCC	WAS →	+0.414	+0.123	<.001	<.001	3	4
LSCC	GPSM3 →	+0.395	+0.148	<.001	.001	3	4
LSCC	EVL →	+0.574	+0.124	<.001	<.001	3	4
LSCC	HCLS1 →	+0.469	+0.117	<.001	<.001	3	4
LSCC	PTPN7 →	+0.428	+0.117	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,945 associations by consensus.

ITIH1 vs VAV1 — LSCC

Explore this scatter interactively →