Across TCGA patient cohorts, ITGBL1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,889 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ITGBL1-associated genes across cancer lineages are MXRA5, CCN4, and PCOLCE. Each is linked with ITGBL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ITGBL1-to-partner and partner-to-ITGBL1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGBL1→partner) and Y-score (partner→ITGBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MXRA5 →	+1.526	+1.021	<.001	<.001	3	6
GBM	CCN4 →	+1.813	+0.881	<.001	<.001	3	6
GBM	PCOLCE →	+1.281	+0.851	<.001	<.001	3	6
BRCA	AEBP1 →	+1.887	+1.228	<.001	<.001	3	6
BRCA	ASPN →	+2.351	+1.225	<.001	<.001	3	6
GBM	COL1A1 →	+2.732	+1.100	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,889 associations by consensus.

Exploration

ITGBL1 survival (RNA) · tumor vs normal (RNA) · all ITGBL1 data types