Across TCGA patient cohorts, ITGBL1 mutation is significantly associated with the RNA expression of many other genes, with 1,541 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ITGBL1-associated genes across cancer lineages are DDX11-AS1, OR2G3, and CIDECP1. Each is linked with ITGBL1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ITGBL1-to-partner and partner-to-ITGBL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGBL1→partner) and Y-score (partner→ITGBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	DDX11-AS1 →	+0.421	+3.504	.006	.002	3	4
COAD	OR2G3 →	+0.030	+4.392	.002	.006	3	3
UCEC	CIDECP1 →	+0.541	+3.016	<.001	<.001	3	3
UCEC	SHLD3 →	+0.480	+1.858	<.001	.005	3	3
LUSC	BNIP1 →	+0.400	+3.339	.001	.005	3	3
LUSC	GKAP1 →	+0.682	+3.503	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,541 associations by consensus.

Exploration

ITGBL1 survival (RNA) · tumor vs normal (RNA) · all ITGBL1 data types