Across TCGA patient cohorts, ITGBL1 mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ITGBL1-associated genes across cancer lineages are Caveolin-1, Notch1, and ATM. Each is linked with ITGBL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ITGBL1-to-partner and partner-to-ITGBL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGBL1→partner) and Y-score (partner→ITGBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Caveolin-1 →	-0.858	-3.000	.031	.036	3	2
UCEC	Notch1 →	+0.224	+2.594	<.001	.006	3	2
UCEC	ATM →	-0.600	-2.321	.001	.006	3	2
UCEC	Bak →	+0.253	+1.807	.014	.027	3	2
UCEC	Caspase-8 →	-0.224	-3.432	.031	.005	3	2
LUAD	P-Cadherin →	+0.269	+3.016	.019	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

Exploration

ITGBL1 survival (RNA) · tumor vs normal (RNA) · all ITGBL1 data types