Across TCGA cell cohorts, ITGBL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,605 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ITGBL1-associated GO terms across cancer lineages are Canonical NF-kappaB signal transduction, Regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway, and Activation of blood coagulation via clotting cascade. Each is linked with ITGBL1 in more than 9 cancer types. Because this analysis shows association rather than direction, both ITGBL1-to-partner and partner-to-ITGBL1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGBL1→partner) and Y-score (partner→ITGBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Canonical NF-kappaB signal transduction →	+0.078	+3.350	<.001	<.001	3	10
BONE	Regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.128	+3.269	<.001	<.001	3	10
BREAST	Activation of blood coagulation via clotting cascade →	+0.393	+1.957	.001	.001	3	10
BONE	Positive regulation of canonical NF-kappaB signal transduction →	+0.067	+3.875	<.001	<.001	3	10
BONE	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.184	+3.843	<.001	<.001	3	10
BREAST	Antigen processing and presentation of exogenous peptide antigen via MHC class Ib →	+0.326	+2.622	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,605 associations by consensus.

Exploration

ITGBL1 survival (RNA) · tumor vs normal (RNA) · all ITGBL1 data types