Across TCGA cell cohorts, ITGBL1 mutation is significantly associated with the RNA expression of many other genes, with 259 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ITGBL1-associated genes across cancer lineages are NOP53, EIF4B, and RPL3. Each is linked with ITGBL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ITGBL1-to-partner and partner-to-ITGBL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGBL1→partner) and Y-score (partner→ITGBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NOP53 →	+0.625	+3.386	<.001	.001	3	2
LARGE_INTESTINE	EIF4B →	+0.707	+2.628	<.001	.002	3	2
LARGE_INTESTINE	RPL3 →	+0.544	+3.237	<.001	.003	3	1
LARGE_INTESTINE	SAMM50 →	+0.631	+3.523	<.001	<.001	3	1
LARGE_INTESTINE	ST13 →	+0.475	+3.169	.004	.006	3	1
LARGE_INTESTINE	POLR3H →	+0.598	+2.628	.007	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 259 associations by consensus.

Exploration

ITGBL1 survival (RNA) · tumor vs normal (RNA) · all ITGBL1 data types