ITGB8

Across TCGA patient cohorts, ITGB8 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,199 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ITGB8-associated proteins across cancer lineages are EGFR, SEC24C, and TRIM2. Each is linked with ITGB8 in more than 5 cancer types. Because this analysis shows association rather than direction, both ITGB8-to-partner and partner-to-ITGB8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGB8 versus EGFR in GBM, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB8→partner) and Y-score (partner→ITGB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EGFR →	+1.031	+0.537	<.001	<.001	3	6
BRCA	SEC24C →	-0.232	-1.408	<.001	<.001	3	5
BRCA	TRIM2 →	+0.584	+1.325	<.001	<.001	3	4
BRCA	PSAT1 →	+1.545	+1.330	<.001	<.001	3	4
PDAC	PTPN14_S594 →	+0.563	+0.714	.001	.002	3	4
BRCA	XRN2_S448 →	-0.825	-0.999	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,199 associations by consensus.

ITGB8 vs EGFR — GBM

Explore this scatter interactively →