ITGB8

Across TCGA cell cohorts, ITGB8 RNA expression is significantly associated with the RNA expression of many other genes, with 10,142 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ITGB8-associated genes across cancer lineages are MAML2, LCA5, and PARP14. Each is linked with ITGB8 in more than 8 cancer types. Because this analysis shows association rather than direction, both ITGB8-to-partner and partner-to-ITGB8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGB8 versus MAML2 in PANCREAS, with a Pearson correlation of 0.60.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB8→partner) and Y-score (partner→ITGB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	MAML2 →	+1.654	+2.419	<.001	<.001	2	9
LUNG_SCLC	LCA5 →	+1.326	+2.739	<.001	<.001	3	7
BREAST	PARP14 →	+1.973	+2.418	<.001	<.001	3	7
BREAST	CD109 →	+2.283	+1.531	<.001	<.001	3	7
LUNG_NSCLC_LUSC	FAM3C →	+1.343	+2.468	.004	<.001	2	8
PANCREAS	LCN2 →	+4.943	+1.963	.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,142 associations by consensus.

ITGB8 vs MAML2 — PANCREAS

Explore this scatter interactively →