ITGB8

Across TCGA cell cohorts, ITGB8 mutation is significantly associated with the drug of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ITGB8-associated genes across cancer lineages are Mirin, CD532, and 150412. Each is linked with ITGB8 in more than 1 cancer types. Because this analysis shows association rather than direction, both ITGB8-to-partner and partner-to-ITGB8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mirin grouped by ITGB8-low versus ITGB8-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB8→partner) and Y-score (partner→ITGB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Mirin →	+0.472	+2.646	.011	.047	3	1
LARGE_INTESTINE	CD532 →	+0.432	+2.652	.031	.045	3	1
LARGE_INTESTINE	150412 →	+0.418	+2.777	.012	.038	2	1
LARGE_INTESTINE	50869 →	+0.484	+2.649	.021	.046	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Mirin by ITGB8 expression — LARGE_INTESTINE

Explore this box plot interactively →