ITGB7

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ITGB7 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,674 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ITGB7-associated proteins across cancer lineages are NCF4, ARHGAP45, and BTK. Each is linked with ITGB7 in more than 9 cancer types. Because this analysis shows association rather than direction, both ITGB7-to-partner and partner-to-ITGB7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGB7 versus NCF4 in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB7→partner) and Y-score (partner→ITGB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMNCF4 →+0.630+0.362<.001<.001310
LSCCARHGAP45 →+0.529+0.589<.001<.001310
COADBTK →+0.745+0.581<.001.001310
BRCACORO1A →+0.671+0.932<.001<.001310
LSCCDOCK8 →+0.505+0.614<.001<.001310
COADGPSM3 →+0.566+0.622<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,674 associations by consensus.

ITGB7 vs NCF4 — GBM

Per-sample scatter of ITGB7 vs NCF4 in GBM (Pearson r = 0.47).

Explore this scatter interactively →

Exploration