ITGB7

Across TCGA patient cohorts, ITGB7 protein abundance is significantly associated with the RNA expression of many other genes, with 9,719 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ITGB7-associated genes across cancer lineages are JAK3, GPR174, and PYHIN1. Each is linked with ITGB7 in more than 5 cancer types. Because this analysis shows association rather than direction, both ITGB7-to-partner and partner-to-ITGB7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGB7 versus JAK3 in BRCA, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB7→partner) and Y-score (partner→ITGB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	JAK3 →	+1.455	+0.778	<.001	<.001	3	6
UCEC	GPR174 →	+1.582	+0.954	.003	.005	3	6
BRCA	PYHIN1 →	+1.183	+0.694	.004	.002	3	6
UCEC	CD3D →	+2.021	+1.136	.006	<.001	3	6
BRCA	PRF1 →	+1.815	+0.752	<.001	.002	3	6
UCEC	TIGIT →	+1.558	+1.159	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,719 associations by consensus.

ITGB7 vs JAK3 — BRCA

Explore this scatter interactively →