ITGB4

Across TCGA patient cohorts, ITGB4 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,907 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ITGB4-associated proteins across cancer lineages are ITGB4_T1530, ITGA6, and ITGB4_S1069. Each is linked with ITGB4 in more than 7 cancer types. Because this analysis shows association rather than direction, both ITGB4-to-partner and partner-to-ITGB4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGB4 versus ITGB4_T1530 in LSCC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB4→partner) and Y-score (partner→ITGB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ITGB4_T1530 →	+1.227	+1.015	<.001	<.001	3	8
LSCC	ITGA6 →	+0.736	+1.056	<.001	<.001	3	6
BRCA	ITGB4_S1069 →	+1.302	+1.119	.002	.001	3	6
LSCC	ITGB4_S1547 →	+1.290	+1.454	<.001	<.001	3	6
LSCC	LAMB3 →	+0.928	+1.037	<.001	<.001	3	6
LSCC	LAMC2 →	+1.033	+1.004	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,907 associations by consensus.

ITGB4 vs ITGB4_T1530 — LSCC

Explore this scatter interactively →