ITGB3

Across TCGA patient cohorts, ITGB3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,189 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ITGB3-associated proteins across cancer lineages are ITGAV, MMP14, and ITGA3. Each is linked with ITGB3 in more than 7 cancer types. Because this analysis shows association rather than direction, both ITGB3-to-partner and partner-to-ITGB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGB3 versus ITGAV in OV, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB3→partner) and Y-score (partner→ITGB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ITGAV →	+0.637	+1.431	.001	.001	3	8
BRCA	MMP14 →	+0.592	+0.538	<.001	.006	3	8
GBM	ITGA3 →	+0.903	+1.062	<.001	<.001	3	7
LSCC	ITGA5 →	+0.479	+0.750	<.001	<.001	3	7
COAD	ITGB1 →	+0.409	+0.651	<.001	<.001	3	7
PDAC	LOXL2 →	+0.810	+0.673	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,189 associations by consensus.

ITGB3 vs ITGAV — OV

Explore this scatter interactively →