ITGB3

Across TCGA patient cohorts, ITGB3 protein abundance is significantly associated with the RNA expression of many other genes, with 9,182 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ITGB3-associated genes across cancer lineages are RNU7-186P, NRP1, and GPRC5A. Each is linked with ITGB3 in more than 4 cancer types. Because this analysis shows association rather than direction, both ITGB3-to-partner and partner-to-ITGB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGB3 versus RNU7-186P in OV, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB3→partner) and Y-score (partner→ITGB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RNU7-186P →	+1.705	+0.575	.001	.003	3	5
UCEC	NRP1 →	+0.809	+0.537	.001	.002	3	5
OV	GPRC5A →	+1.370	+0.511	.001	.006	3	4
GBM	SOCS3 →	+1.886	+1.061	<.001	<.001	3	4
OV	RBMS2 →	+0.675	+0.462	.003	.006	3	4
UCEC	MRPS26 →	-1.097	-0.496	.001	.006	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,182 associations by consensus.

ITGB3 vs RNU7-186P — OV

Explore this scatter interactively →