ITGB2

Across TCGA patient cohorts, ITGB2 RNA expression is significantly associated with the RNA expression of many other genes, with 16,775 significant associations in total. UVM shows the largest number of these associations.

The most reproducible ITGB2-associated genes across cancer lineages are JAML, SNX20, and LAIR1. Each is linked with ITGB2 in more than 33 cancer types. Because this analysis shows association rather than direction, both ITGB2-to-partner and partner-to-ITGB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGB2 versus JAML in LAML, with a Pearson correlation of 0.73.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB2→partner) and Y-score (partner→ITGB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	JAML →	+2.358	+1.808	<.001	<.001	3	34
SKCM	SNX20 →	+2.094	+2.526	<.001	<.001	3	34
SARC	LAIR1 →	+2.307	+2.490	<.001	<.001	3	34
LAML	SIGLEC7 →	+2.213	+1.986	<.001	<.001	3	34
SARC	FMNL1 →	+1.898	+2.173	<.001	<.001	3	34
DLBC	C16orf54 →	+2.226	+1.324	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,775 associations by consensus.

ITGB2 vs JAML — LAML

Explore this scatter interactively →