ITGB2

Across TCGA patient cohorts, ITGB2 protein abundance is significantly associated with the RNA expression of many other genes, with 19,617 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ITGB2-associated genes across cancer lineages are CSF2RB, SIRPB1, and HCK. Each is linked with ITGB2 in more than 9 cancer types. Because this analysis shows association rather than direction, both ITGB2-to-partner and partner-to-ITGB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGB2 versus CSF2RB in BRCA, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB2→partner) and Y-score (partner→ITGB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CSF2RB →	+1.539	+0.779	<.001	<.001	3	10
HNSC	SIRPB1 →	+0.736	+0.608	<.001	<.001	3	10
GBM	HCK →	+1.250	+0.822	<.001	<.001	3	10
GBM	TLR8 →	+1.165	+0.683	<.001	<.001	3	10
GBM	LILRB1 →	+1.132	+0.797	<.001	<.001	3	10
GBM	CD33 →	+0.977	+0.793	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,617 associations by consensus.

ITGB2 vs CSF2RB — BRCA

Explore this scatter interactively →