ITGB1

Across TCGA patient cohorts, ITGB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,494 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ITGB1-associated proteins across cancer lineages are ZYX, MYO1E, and LOX. Each is linked with ITGB1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ITGB1-to-partner and partner-to-ITGB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGB1 versus ZYX in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB1→partner) and Y-score (partner→ITGB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZYX →	+0.597	+0.766	<.001	<.001	3	9
OV	MYO1E →	+0.404	+0.769	<.001	<.001	3	9
OV	LOX →	+1.019	+0.775	<.001	.001	3	9
OV	ITGA5 →	+0.837	+1.122	<.001	<.001	3	9
BRCA	TES_S168 →	+0.688	+0.489	<.001	.009	3	8
CCRCC	THBS1 →	+0.971	+0.522	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,494 associations by consensus.

ITGB1 vs ZYX — OV

Explore this scatter interactively →