ITGB1

Across TCGA patient cohorts, ITGB1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,537 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ITGB1-associated genes across cancer lineages are MYL9, ACTA2, and CNN1. Each is linked with ITGB1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ITGB1-to-partner and partner-to-ITGB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGB1 versus MYL9 in OV, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB1→partner) and Y-score (partner→ITGB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MYL9 →	+1.239	+0.408	<.001	<.001	3	9
OV	ACTA2 →	+1.520	+0.386	<.001	<.001	3	9
COAD	CNN1 →	+1.680	+0.396	<.001	<.001	3	9
CCRCC	TAGLN →	+1.423	+0.243	<.001	<.001	3	9
OV	SPARC →	+1.822	+0.488	<.001	<.001	3	8
OV	LOXL2 →	+1.545	+0.424	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,537 associations by consensus.

ITGB1 vs MYL9 — OV

Explore this scatter interactively →