ITGB1

Across TCGA cell cohorts, ITGB1 RNA expression is significantly associated with the RNA expression of many other genes, with 12,947 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ITGB1-associated genes across cancer lineages are HERC4, PLIN3, and RTN4. Each is linked with ITGB1 in more than 15 cancer types. Because this analysis shows association rather than direction, both ITGB1-to-partner and partner-to-ITGB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGB1 versus HERC4 in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.64.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB1→partner) and Y-score (partner→ITGB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	HERC4 →	+1.450	+1.281	<.001	<.001	3	16
BONE	PLIN3 →	+2.098	+2.729	<.001	<.001	3	16
LIVER	RTN4 →	+1.358	+2.115	.001	<.001	3	15
BONE	CRIM1 →	+2.608	+1.601	<.001	<.001	3	14
LUNG_NSCLC_LUSC	GPX8 →	+2.608	+1.343	<.001	<.001	3	14
LUNG_NSCLC_LUSC	AXL →	+4.339	+1.606	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,947 associations by consensus.

ITGB1 vs HERC4 — LUNG_NSCLC_LUSC

Explore this scatter interactively →