ITGB1

Across TCGA cell cohorts, ITGB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,599 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ITGB1-associated GO terms across cancer lineages are Regulation of glutamate uptake involved in transmission of nerve impulse, Epiboly, and Positive regulation of cell-substrate adhesion. Each is linked with ITGB1 in more than 17 cancer types. Because this analysis shows association rather than direction, both ITGB1-to-partner and partner-to-ITGB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of glutamate uptake involved in transmission of nerve impulse grouped by ITGB1-low versus ITGB1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB1→partner) and Y-score (partner→ITGB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of glutamate uptake involved in transmission of nerve impulse →	+0.295	+2.099	<.001	<.001	3	18
BREAST	Epiboly →	+0.153	+1.663	<.001	<.001	3	17
BONE	Positive regulation of cell-substrate adhesion →	+0.151	+1.942	<.001	<.001	3	17
BONE	Positive regulation of cell-matrix adhesion →	+0.164	+1.926	<.001	<.001	3	17
BONE	Positive regulation of focal adhesion assembly →	+0.193	+1.775	<.001	<.001	3	17
KIDNEY	Wound healing, spreading of epidermal cells →	+0.318	+1.238	<.001	.003	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,599 associations by consensus.

Regulation of glutamate uptake involved in transmission of nerve impulse by ITGB1 expression — LIVER

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