ITGAX

Across TCGA patient cohorts, ITGAX RNA expression is significantly associated with the protein abundance of many other proteins, with 20,506 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ITGAX-associated proteins across cancer lineages are SKAP2, SPN, and STK10. Each is linked with ITGAX in more than 9 cancer types. Because this analysis shows association rather than direction, both ITGAX-to-partner and partner-to-ITGAX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGAX versus SKAP2 in UCEC, with a Pearson correlation of 0.77.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGAX→partner) and Y-score (partner→ITGAX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SKAP2 →	+0.846	+1.043	<.001	<.001	3	10
GBM	SPN →	+0.732	+0.991	<.001	<.001	3	10
OV	STK10 →	+0.539	+1.325	<.001	<.001	3	10
OV	STK4 →	+0.417	+0.905	.002	.005	3	10
UCEC	STX11 →	+0.748	+0.846	<.001	<.001	3	10
COAD	TNFAIP8L2 →	+0.743	+1.241	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,506 associations by consensus.

ITGAX vs SKAP2 — UCEC

Explore this scatter interactively →