ITGAX

Across TCGA cell cohorts, ITGAX RNA expression is significantly associated with the go_rna of many other GO terms, with 4,613 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ITGAX-associated GO terms across cancer lineages are Protein folding, Viral process, and Biological process involved in symbiotic interaction. Each is linked with ITGAX in more than 10 cancer types. Because this analysis shows association rather than direction, both ITGAX-to-partner and partner-to-ITGAX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein folding grouped by ITGAX-low versus ITGAX-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGAX→partner) and Y-score (partner→ITGAX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein folding →	+0.077	+1.374	<.001	.001	3	11
SOFT_TISSUE	Viral process →	+0.080	+1.004	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Biological process involved in symbiotic interaction →	+0.083	+0.808	.003	.003	3	11
PANCREAS	Positive regulation of innate immune response →	+0.054	+0.509	<.001	.004	3	10
BLOOD_Lymphoma	Intestinal epithelial cell development →	+0.558	+1.362	.002	.004	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of release of cytochrome c from mitochondria →	+0.102	+0.585	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,613 associations by consensus.

Protein folding by ITGAX expression — OESOPHAGUS

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