ITGAD

Across TCGA cell cohorts, ITGAD RNA expression is significantly associated with the go_rna of many other GO terms, with 571 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ITGAD-associated GO terms across cancer lineages are Glycosphingolipid metabolic process, Negative regulation of type I interferon production, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with ITGAD in more than 4 cancer types. Because this analysis shows association rather than direction, both ITGAD-to-partner and partner-to-ITGAD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycosphingolipid metabolic process grouped by ITGAD-low versus ITGAD-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGAD→partner) and Y-score (partner→ITGAD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Glycosphingolipid metabolic process →	+0.033	+0.241	.001	.008	3	5
UPPER_AERODIGESTIVE_TRACT	Negative regulation of type I interferon production →	+0.079	+0.016	<.001	.002	3	4
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.086	+0.015	.002	.004	3	4
BLOOD_Lymphoma	Cotranslational protein targeting to membrane →	+0.082	+0.318	.001	.002	3	4
LUNG_NSCLC_LUAD	Detection of external stimulus →	-0.041	-0.041	.005	.006	3	4
BLOOD_Lymphoma	Detection of abiotic stimulus →	-0.044	-0.425	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 571 associations by consensus.

Glycosphingolipid metabolic process by ITGAD expression — BLOOD_Lymphoma

Explore this box plot interactively →