ITGA9

Across TCGA pan-cancer cohorts, ITGA9 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated ITGA9 data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ITGA9 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ITGA9 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PDAC show a favorable association.

COAD, HNSC, and PDAC are the cancer types where ITGA9 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.855	1.000	.010	72	view →
HNSC	DFS	Tertile	III,IV	0.931	0.596	<.001	25	view →
PDAC	DFS	Median	III,IV	0.585	0.220	.012	9	view →
OV	DFS	Tertile	All	0.441	0.884	.018	8	view →
UCEC	DFS	Median	All	0.784	0.935	.029	8	view →
CCRCC	OS	Median	All	1.000	0.681	.010	4	view →
LUAD	OS	Quartile	II,III,IV	0.797	0.379	.016	4	view →
GBM	DFS	Median	All	0.416	0.207	.030	2	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

ITGA9–COAD (DFS)

Open the COAD breakdown →