ITGA9

Across TCGA patient cohorts, ITGA9 mutation is significantly associated with the RNA expression of many other genes, with 3,472 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ITGA9-associated genes across cancer lineages are MIR8064, RPL34P19, and MCAT. Each is linked with ITGA9 in more than 2 cancer types. Because this analysis shows association rather than direction, both ITGA9-to-partner and partner-to-ITGA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8064 grouped by ITGA9-low versus ITGA9-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA9→partner) and Y-score (partner→ITGA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MIR8064 →	+0.667	+4.169	<.001	.001	3	3
SKCM	RPL34P19 →	+0.151	+3.018	<.001	<.001	3	3
UCEC	MCAT →	+0.353	+2.330	<.001	<.001	3	3
UCEC	MCM5 →	+0.480	+3.108	.001	<.001	3	3
UCEC	CDT1 →	+0.769	+2.447	<.001	<.001	3	3
UCEC	FEN1 →	+0.579	+4.010	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,472 associations by consensus.

MIR8064 by ITGA9 expression — LUSC

Explore this box plot interactively →