ITGA9

Across TCGA cell cohorts, ITGA9 mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ITGA9-associated genes across cancer lineages are GALP, PITX3, and CAPRIN1. Each is linked with ITGA9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ITGA9-to-partner and partner-to-ITGA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GALP grouped by ITGA9-low versus ITGA9-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA9→partner) and Y-score (partner→ITGA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GALP →	+0.027	+3.201	<.001	.005	3	2
LARGE_INTESTINE	PITX3 →	+0.166	+2.906	<.001	.004	3	1
LARGE_INTESTINE	CAPRIN1 →	+0.564	+3.082	.002	.007	3	1
LARGE_INTESTINE	LTV1 →	+0.611	+3.082	.003	.007	3	1
LARGE_INTESTINE	CYP2C8 →	+0.251	+3.417	<.001	.004	3	1
LARGE_INTESTINE	DDX52 →	+0.531	+3.067	.004	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

GALP by ITGA9 expression — BLOOD_Leukemia

Explore this box plot interactively →