ITGA8

Across TCGA patient cohorts, ITGA8 protein abundance is significantly associated with the RNA expression of many other genes, with 7,578 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ITGA8-associated genes across cancer lineages are TCF21, MS4A2, and ANGPT1. Each is linked with ITGA8 in more than 3 cancer types. Because this analysis shows association rather than direction, both ITGA8-to-partner and partner-to-ITGA8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGA8 versus TCF21 in UCEC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA8→partner) and Y-score (partner→ITGA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TCF21 →	+0.741	+0.357	.001	.001	3	4
UCEC	MS4A2 →	+1.017	+0.336	<.001	.002	3	4
UCEC	ANGPT1 →	+0.932	+0.533	<.001	<.001	3	4
UCEC	PIEZO2 →	+1.045	+0.377	.001	.006	3	4
UCEC	TPSAB1 →	+1.631	+0.530	.006	<.001	3	4
PDAC	MYOCD →	+0.790	+0.817	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,578 associations by consensus.

ITGA8 vs TCF21 — UCEC

Explore this scatter interactively →