ITGA6

Across TCGA patient cohorts, ITGA6 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,586 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ITGA6-associated proteins across cancer lineages are ITGB4, SEPTIN10, and ITGB4_S1069. Each is linked with ITGA6 in more than 6 cancer types. Because this analysis shows association rather than direction, both ITGA6-to-partner and partner-to-ITGA6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGA6 versus ITGB4 in LSCC, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA6→partner) and Y-score (partner→ITGA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ITGB4 →	+0.759	+1.132	<.001	<.001	3	7
LSCC	SEPTIN10 →	+0.363	+0.721	<.001	.002	3	6
BRCA	ITGB4_S1069 →	+2.431	+1.628	<.001	<.001	3	6
LSCC	ITGB4_T1530 →	+1.066	+0.933	<.001	<.001	3	6
PDAC	ASAP2_S822 →	+0.379	+0.379	<.001	<.001	3	5
OV	ITGB4_S1547 →	+1.179	+0.800	.001	.008	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,586 associations by consensus.

ITGA6 vs ITGB4 — LSCC

Explore this scatter interactively →