ITGA6

Across TCGA patient cohorts, ITGA6 protein abundance is significantly associated with the RNA expression of many other genes, with 13,955 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ITGA6-associated genes across cancer lineages are ITGA6-AS1, ITGB4, and CHRDL1. Each is linked with ITGA6 in more than 6 cancer types. Because this analysis shows association rather than direction, both ITGA6-to-partner and partner-to-ITGA6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGA6 versus ITGA6-AS1 in HNSC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA6→partner) and Y-score (partner→ITGA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ITGA6-AS1 →	+1.115	+0.741	<.001	<.001	3	7
BRCA	ITGB4 →	+1.210	+0.565	<.001	<.001	3	6
CCRCC	CHRDL1 →	-2.030	-0.360	<.001	<.001	3	5
BRCA	ETS2 →	+0.888	+0.532	<.001	<.001	3	5
COAD	KCNAB2 →	-0.577	-0.405	<.001	.001	3	5
UCEC	BTK →	-0.824	-0.600	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,955 associations by consensus.

ITGA6 vs ITGA6-AS1 — HNSC

Explore this scatter interactively →