ITGA6

Across TCGA cell cohorts, ITGA6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,525 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ITGA6-associated GO terms across cancer lineages are Nail development, Ectodermal cell differentiation, and Positive regulation of transmission of nerve impulse. Each is linked with ITGA6 in more than 18 cancer types. Because this analysis shows association rather than direction, both ITGA6-to-partner and partner-to-ITGA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nail development grouped by ITGA6-low versus ITGA6-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA6→partner) and Y-score (partner→ITGA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nail development →	+1.575	+3.461	<.001	<.001	3	19
BONE	Ectodermal cell differentiation →	+1.475	+2.826	<.001	<.001	3	18
STOMACH	Positive regulation of transmission of nerve impulse →	+1.611	+2.535	<.001	.002	3	9
BONE	Cellular response to environmental stimulus →	+0.046	+2.033	<.001	.001	3	9
URINARY_TRACT	Regulation of blood coagulation →	+0.153	+1.932	.001	.008	3	9
BONE	Cellular response to abiotic stimulus →	+0.046	+2.033	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,525 associations by consensus.

Nail development by ITGA6 expression — BONE

Explore this box plot interactively →