ITGA3

Across TCGA patient cohorts, ITGA3 protein abundance is significantly associated with the RNA expression of many other genes, with 18,544 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ITGA3-associated genes across cancer lineages are PICART1, ITGB3, and OSMR. Each is linked with ITGA3 in more than 7 cancer types. Because this analysis shows association rather than direction, both ITGA3-to-partner and partner-to-ITGA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGA3 versus PICART1 in LSCC, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA3→partner) and Y-score (partner→ITGA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PICART1 →	+0.722	+0.590	<.001	<.001	3	8
UCEC	ITGB3 →	+1.201	+0.675	<.001	<.001	3	7
GBM	OSMR →	+0.908	+0.523	<.001	<.001	3	6
LSCC	AHNAK2 →	+1.344	+0.440	<.001	.001	3	6
GBM	CAV2 →	+0.885	+0.636	<.001	<.001	3	6
GBM	CAV1 →	+1.634	+0.825	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,544 associations by consensus.

ITGA3 vs PICART1 — LSCC

Explore this scatter interactively →