ITGA3

Across TCGA cell cohorts, ITGA3 mutation is significantly associated with the RNA expression of many other genes, with 532 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ITGA3-associated genes across cancer lineages are MYF5, OR1N1, and FAM205A. Each is linked with ITGA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ITGA3-to-partner and partner-to-ITGA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYF5 grouped by ITGA3-low versus ITGA3-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA3→partner) and Y-score (partner→ITGA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	MYF5 →	+0.023	+5.169	<.001	.005	3	2
OVARY	OR1N1 →	+0.298	+3.263	.001	.006	3	2
LARGE_INTESTINE	FAM205A →	+0.020	+3.029	<.001	.002	3	2
BLOOD_Myeloma	C20orf173 →	+0.026	+3.285	<.001	.009	3	1
BLOOD_Myeloma	HBZ →	+0.038	+3.716	<.001	.005	3	1
URINARY_TRACT	OR2A2 →	+0.046	+5.087	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 532 associations by consensus.

MYF5 by ITGA3 expression — BREAST

Explore this box plot interactively →