ITGA2B

Across TCGA patient cohorts, ITGA2B RNA expression is significantly associated with the protein abundance of many other proteins, with 8,601 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ITGA2B-associated proteins across cancer lineages are TRIP13, SMG8, and SGSM3. Each is linked with ITGA2B in more than 4 cancer types. Because this analysis shows association rather than direction, both ITGA2B-to-partner and partner-to-ITGA2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGA2B versus TRIP13 in LSCC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA2B→partner) and Y-score (partner→ITGA2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TRIP13 →	+0.592	+0.652	<.001	<.001	3	5
LSCC	SMG8 →	+0.204	+0.566	.001	.002	3	4
PDAC	SGSM3 →	-0.339	-0.197	.001	.001	3	4
LSCC	COIL →	+0.449	+0.645	<.001	<.001	3	4
LSCC	FXR1 →	+0.381	+0.530	<.001	<.001	3	4
LUAD	MCM2 →	+0.553	+0.569	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,601 associations by consensus.

ITGA2B vs TRIP13 — LSCC

Explore this scatter interactively →