ITGA2B

Across TCGA cell cohorts, ITGA2B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,749 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ITGA2B-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Cytoplasmic translation, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with ITGA2B in more than 17 cancer types. Because this analysis shows association rather than direction, both ITGA2B-to-partner and partner-to-ITGA2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by ITGA2B-low versus ITGA2B-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA2B→partner) and Y-score (partner→ITGA2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.213	+1.630	<.001	<.001	3	18
OESOPHAGUS	Cytoplasmic translation →	+0.160	+1.734	<.001	<.001	3	17
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.214	+1.630	<.001	<.001	3	17
OESOPHAGUS	Aerobic respiration →	+0.145	+1.727	<.001	<.001	3	15
OESOPHAGUS	Regulation of myoblast fusion →	+0.190	+1.630	<.001	<.001	3	15
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.130	+1.293	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,749 associations by consensus.

Negative regulation of myoblast fusion by ITGA2B expression — OESOPHAGUS

Explore this box plot interactively →