ITGA2

Across TCGA patient cohorts, ITGA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,555 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ITGA2-associated proteins across cancer lineages are ITGB1, COL17A1, and PLS3. Each is linked with ITGA2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ITGA2-to-partner and partner-to-ITGA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGA2 versus ITGB1 in PDAC, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA2→partner) and Y-score (partner→ITGA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ITGB1 →	+0.357	+0.523	<.001	.001	3	5
UCEC	COL17A1 →	+1.528	+1.738	.008	.005	3	5
GBM	PLS3 →	+0.617	+1.232	<.001	<.001	3	5
OV	S100A11 →	+0.511	+0.993	.001	.001	3	4
LSCC	BCAR1 →	+0.290	+0.894	.002	.005	3	4
LUAD	EGFR_S1064 →	+1.386	+1.517	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,555 associations by consensus.

ITGA2 vs ITGB1 — PDAC

Explore this scatter interactively →