ITGA2

Across TCGA cell cohorts, ITGA2 RNA expression is significantly associated with the RNA expression of many other genes, with 9,364 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ITGA2-associated genes across cancer lineages are SMAD3, TRIM8, and SLC37A2. Each is linked with ITGA2 in more than 10 cancer types. Because this analysis shows association rather than direction, both ITGA2-to-partner and partner-to-ITGA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGA2 versus SMAD3 in SOFT_TISSUE, with a Pearson correlation of 0.61.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA2→partner) and Y-score (partner→ITGA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	SMAD3 →	+1.623	+2.469	<.001	<.001	3	11
BONE	TRIM8 →	+1.125	+1.449	.004	.003	3	10
PANCREAS	SLC37A2 →	+4.113	+2.190	<.001	<.001	3	10
BREAST	EGFR →	+3.082	+2.118	<.001	<.001	3	10
BREAST	TGFBR2 →	+2.441	+1.731	<.001	<.001	3	10
LUNG_NSCLC_LUSC	CREG2 →	+2.052	+2.366	<.001	.005	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,364 associations by consensus.

ITGA2 vs SMAD3 — SOFT_TISSUE

Explore this scatter interactively →