ITGA11

Across TCGA patient cohorts, ITGA11 mutation is significantly associated with the RNA expression of many other genes, with 3,076 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ITGA11-associated genes across cancer lineages are NOL4L, LINC00954, and EIF4EBP3. Each is linked with ITGA11 in more than 3 cancer types. Because this analysis shows association rather than direction, both ITGA11-to-partner and partner-to-ITGA11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NOL4L grouped by ITGA11-low versus ITGA11-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA11→partner) and Y-score (partner→ITGA11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	NOL4L →	-0.830	-3.807	<.001	<.001	3	3
COAD	LINC00954 →	-0.341	-2.401	.008	.003	3	3
COAD	EIF4EBP3 →	-0.885	-2.415	<.001	.003	3	3
COAD	C17orf113 →	-0.544	-2.388	.001	.003	3	3
LIHC	MTCO2P23 →	+0.050	+5.902	<.001	.001	3	3
BRCA	RNA5SP421 →	+0.157	+5.145	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,076 associations by consensus.

NOL4L by ITGA11 expression — COAD

Explore this box plot interactively →