ITGA11

Across TCGA cell cohorts, ITGA11 mutation is significantly associated with the RNA expression of many other genes, with 197 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ITGA11-associated genes across cancer lineages are IPP, BCL2L10, and ABCA12. Each is linked with ITGA11 in more than 1 cancer types. Because this analysis shows association rather than direction, both ITGA11-to-partner and partner-to-ITGA11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IPP grouped by ITGA11-low versus ITGA11-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA11→partner) and Y-score (partner→ITGA11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	IPP →	+0.594	+3.321	<.001	.003	3	2
BLOOD_Leukemia	BCL2L10 →	+1.115	+3.378	.002	.008	3	2
BLOOD_Leukemia	ABCA12 →	+0.941	+3.824	<.001	.001	3	2
BLOOD_Leukemia	UCMA →	+0.046	+2.604	.001	.006	3	2
BLOOD_Leukemia	TRIM49B →	+0.059	+2.967	<.001	.003	3	2
LUNG_SCLC	KIR3DL1 →	+0.012	+5.614	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 197 associations by consensus.

IPP by ITGA11 expression — LARGE_INTESTINE

Explore this box plot interactively →