Across TCGA patient cohorts, ITGA1 mutation is significantly associated with the RNA expression of many other genes, with 4,014 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ITGA1-associated genes across cancer lineages are PANK4, LMF2, and ATF4. Each is linked with ITGA1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ITGA1-to-partner and partner-to-ITGA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA1→partner) and Y-score (partner→ITGA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PANK4 →	+0.329	+2.375	<.001	<.001	3	3
UCEC	LMF2 →	+0.426	+3.395	<.001	<.001	3	3
UCEC	ATF4 →	+0.326	+1.354	<.001	.003	3	3
UCEC	ERP27 →	-0.780	-1.635	.004	.005	2	4
UCEC	EVI5L →	+0.459	+2.758	<.001	<.001	3	3
LUAD	TSPY26P →	-0.687	-3.459	.009	.005	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,014 associations by consensus.

Exploration

ITGA1 survival (RNA) · tumor vs normal (RNA) · all ITGA1 data types