Across TCGA patient cohorts, ITGA1 mutation is significantly associated with the total protein of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ITGA1-associated genes across cancer lineages are p90 RSK, ATM, and Cyclin-B1. Each is linked with ITGA1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ITGA1-to-partner and partner-to-ITGA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA1→partner) and Y-score (partner→ITGA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p90 RSK →	+0.165	+2.502	.002	.001	3	3
COAD	ATM →	-0.707	-3.169	<.001	.017	3	3
UCEC	Cyclin-B1 →	+0.645	+1.736	<.001	<.001	3	3
LUAD	KEAP1 →	+0.522	+2.820	.003	.035	3	2
UCEC	ERK2 →	+0.133	+1.362	.016	.031	3	2
UCEC	FoxM1 →	+0.183	+1.347	.014	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

Exploration

ITGA1 survival (RNA) · tumor vs normal (RNA) · all ITGA1 data types