Across TCGA cell cohorts, ITGA1 mutation is significantly associated with the RNA expression of many other genes, with 799 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ITGA1-associated genes across cancer lineages are OR1J2, GSG1L2, and C5orf67. Each is linked with ITGA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ITGA1-to-partner and partner-to-ITGA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA1→partner) and Y-score (partner→ITGA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR1J2 →	+0.044	+4.635	<.001	.003	3	2
SOFT_TISSUE	GSG1L2 →	+0.299	+4.369	<.001	.008	3	2
OESOPHAGUS	C5orf67 →	+0.333	+4.017	.004	.007	3	2
LARGE_INTESTINE	TRMT10A →	+0.742	+2.628	<.001	.002	3	2
SOFT_TISSUE	CABP2 →	+0.069	+4.369	<.001	.008	3	1
SOFT_TISSUE	OR10H2 →	+0.136	+4.369	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 799 associations by consensus.

Exploration

ITGA1 survival (RNA) · tumor vs normal (RNA) · all ITGA1 data types