Across TCGA cell cohorts, ITGA1 mutation is significantly associated with the mutation status of many other genes, with 5,481 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ITGA1-associated genes across cancer lineages are MYCBP2, SETBP1, and CCDC73. Each is linked with ITGA1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ITGA1-to-partner and partner-to-ITGA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA1→partner) and Y-score (partner→ITGA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	MYCBP2 →	+2.985	+3.562	.008	.008	1	5
LUNG_SCLC	SETBP1 →	+3.115	+3.784	.001	.001	1	5
LARGE_INTESTINE	CCDC73 →	+1.898	+2.327	<.001	<.001	1	5
KIDNEY	ITIH5 →	+4.491	+3.554	.003	.003	1	4
BREAST	RABGAP1 →	+4.297	+4.857	.009	.009	1	4
BLOOD_Leukemia	SALL1 →	+2.669	+2.817	.001	.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,481 associations by consensus.

Exploration

ITGA1 survival (RNA) · tumor vs normal (RNA) · all ITGA1 data types