ITFG2-AS1

Across TCGA pan-cancer cohorts, ITFG2-AS1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of ITFG2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where ITFG2-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ITFG2-AS1 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

THCA, LIHC, and BRCA are the cancer types where ITFG2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ITFG2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	IV	−0.682	<.001	10	view →
LIHC	Male	All	+0.330	<.001	6	view →
BRCA	All	All	−0.302	<.001	6	view →
KIRC	All	All	−0.135	.002	6	view →
BLCA	All	All	+0.391	.021	5	view →
CHOL	All	All	+0.378	.037	2	view →
LUAD	Female	II,III,IV	−0.281	.028	2	view →
COAD	All	All	+0.229	.011	2	view →
LUSC	All	All	+0.168	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

ITFG2-AS1–THCA

Open the THCA breakdown →