ISYNA1

Across TCGA patient cohorts, ISYNA1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,102 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ISYNA1-associated genes across cancer lineages are NYNRIN, SSBP4, and NSUN7. Each is linked with ISYNA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ISYNA1-to-partner and partner-to-ISYNA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ISYNA1 versus NYNRIN in BRCA, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ISYNA1→partner) and Y-score (partner→ISYNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NYNRIN →	+0.917	+0.484	<.001	.001	3	6
GBM	SSBP4 →	+0.538	+0.415	.001	<.001	3	6
CCRCC	NSUN7 →	+0.852	+0.391	<.001	<.001	3	5
HNSC	MCM3AP-AS1 →	+0.499	+0.468	<.001	<.001	3	5
LUAD	TLE2 →	+1.020	+0.418	<.001	<.001	3	5
HNSC	RND2 →	+1.025	+0.644	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,102 associations by consensus.

ISYNA1 vs NYNRIN — BRCA

Explore this scatter interactively →