ISOC1

Across TCGA patient cohorts, ISOC1 RNA expression is significantly associated with the RNA expression of many other genes, with 18,935 significant associations in total. UVM shows the largest number of these associations.

The most reproducible ISOC1-associated genes across cancer lineages are FAF2, TMEM161B, and NUDCD2. Each is linked with ISOC1 in more than 33 cancer types. Because this analysis shows association rather than direction, both ISOC1-to-partner and partner-to-ISOC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ISOC1 versus FAF2 in UVM, with a Pearson correlation of 0.71.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ISOC1→partner) and Y-score (partner→ISOC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	FAF2 →	+0.806	+0.644	<.001	<.001	3	34
UVM	TMEM161B →	+1.161	+0.855	<.001	<.001	3	34
UVM	NUDCD2 →	+1.009	+0.954	<.001	<.001	3	34
UVM	SLC25A40 →	+1.316	+0.993	<.001	<.001	3	34
DLBC	CDC23 →	+1.123	+0.730	<.001	<.001	3	34
UVM	CLINT1 →	+1.487	+0.979	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,935 associations by consensus.

ISOC1 vs FAF2 — UVM

Explore this scatter interactively →