ISG20

Across TCGA patient cohorts, ISG20 protein abundance is significantly associated with the RNA expression of many other genes, with 20,799 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ISG20-associated genes across cancer lineages are CD79A, IFNG, and LAX1. Each is linked with ISG20 in more than 9 cancer types. Because this analysis shows association rather than direction, both ISG20-to-partner and partner-to-ISG20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ISG20 versus CD79A in BRCA, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ISG20→partner) and Y-score (partner→ISG20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CD79A →	+2.052	+0.825	<.001	<.001	3	10
BRCA	IFNG →	+1.243	+0.831	<.001	<.001	3	10
BRCA	LAX1 →	+1.329	+0.813	<.001	<.001	3	10
LSCC	LY9 →	+0.882	+0.597	<.001	<.001	3	10
HNSC	ZBP1 →	+1.569	+0.959	<.001	<.001	3	10
BRCA	IRF4 →	+1.399	+0.792	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,799 associations by consensus.

ISG20 vs CD79A — BRCA

Explore this scatter interactively →